Long term cardiovascular complications of COVID-19

2020 CVD and COVID-19 Grant

Years funded: 2021-2021

As knowledge of the clinical journey faced by people recovering from COVID-19 grows, it has become evident that many symptoms persist long after the resolution of the infection. In particular, shortness of breath, even with minor levels of physical activity, is the most commonly reported persistent symptoms after clearance COVID-19. The cause of this severely limiting symptom is unknown. Preliminary evidence has emerged to suggest that COVID-19 may cause long-term damage to the heart and blood vessels of the lungs (pulmonary arteries).

Specifically, residual scarring of the heart and blockage of the pulmonary arteries has been reported in small studies, however the relationship of these changes to post-COVID breathlessness is unclear. Furthermore, the impact of this damage on long term survival is unknown and is potentially enormous given the number of people who have been affected by COVID-19. In the planned study, we will measure the function of the heart and the pressures within the heart and pulmonary arteries at rest and during exercise in post-COVID patients We are internationally known for research using these methods. Information arising from the study will give major insights into the impact of COVID on the heart & lungs.