.jpeg)
Investigating the role of myocardial fibrosis in atrial fibrillation and heart failure
Dr Sandeep Prabhu, Institution: Baker Heart and Diabetes Institute
Years funded: 2019-2021
Atrial fibrillation (AF), a common electrical disturbance, or arrhythmia, of the heart, and heart failure (HF), a condition where the pumping ability of the heart is reduced, are two growing epidemics worldwide, including Australia. Both conditions co-exist in up to a third of patients, with AF an increasingly recognised cause of HF in many instances. Restoring normal rhythm (sinus rhythm) in these patients can substantially improve and even eliminate HF in selected patients.
HF is often associated with injury to the heart muscle in the form of scarring. This can be detected and quantified by cardiac magnetic resonance imaging (CMR). Recently, a procedure known as catheter ablation (CA) has established itself as a highly effective in restoring sinus rhythm, in patients with HF and AF - improving heart function, reducing hospitalisation and even death. Nonetheless, the optimal patients to benefit remain to be determined. Whilst the lack of scarring conferred a greater benefit as confirmed in the CAMERA-MRI study, the extent to which pre-existing scar from severe HF or previous heart attacks may determine outcome is unclear.
This randomised study will evaluate if patients with HF and scar benefit from
- CA compared standard medical therapy and
- benefit from CA to the same extent as patients without scarring, looking primarily at improvement in heart function and heart failure related hospitalisation at 12 months in addition to improvement in symptoms and functional status.
Time to book a Heart Health Check?
Time to book a Heart Health Check?
Time to book a Heart Health Check?
If you're 45 and over, or 30 and over if you're of Aboriginal or Torres Strait Islander descent, you should book your Heart Health Check today...
Together, we can change the future of heart disease
Together, we can change the future of heart disease
Together, we can change the future of heart disease
The power of your ongoing support can help save lives and keep more families together. Help us continue to fund promising heart research projects by donating today. ...
Health Professional Tools
Health Professional Tools
Health Professional Tools
Guidelines, publications and support for the health professional community....
Heart Health Check Toolkit
Heart Health Check Toolkit
Blueberry chia pot
Blueberry chia pot
Blueberry chia pot
Driving Best Practice CVD Prevention in a Post-COVID World
Driving Best Practice CVD Prevention in a Post-COVID World
Driving Best Practice CVD Prevention in a Post-COVID World
Heart stories
Heart stories
Heart stories
Stories of hope from Australian men and women fighting heart disease....
Italian fish parcels
Italian fish parcels
Italian fish parcels
Atrial Fibrillation (AF) clinical resources
Atrial Fibrillation (AF) clinical resources
Resources and clinical information for health professionals...
Vegetarian recipes
Vegetarian recipes
Vegetarian recipes
Search through our vegetarian recipes...
Novel therapies to avoid brain and kidney injury arising from heart surgery and during sepsis
Novel therapies to avoid brain and kidney injury arising from heart surgery and during sepsis
Associate Professor Yugeesh Lankadeva, Institution: The University of Melbourne...
Seafood recipes
Seafood recipes
Seafood recipes
Find heart healthy seafood recipes...
Developing an innovative chatbot-delivered physical activity intervention
Developing an innovative chatbot-delivered physical activity intervention
Developing an innovative chatbot-delivered physical activity intervention
Professor Corneel Vandelanotte, Institution: Central Queensland University...
Mighty mango smoothie
Mighty mango smoothie
Mighty mango smoothie
Our research stories
Our research stories
Our research stories
We fund amazing researchers who have important stories to tell...
Endorsement of externally developed clinical resources
Endorsement of externally developed clinical resources
Women and heart disease
Women and heart disease
Women and heart disease
Information on women and heart disease for consumers....
Salad recipes
Salad recipes
Salad recipes
Search through our tasty salad recipes...
Systems of care in cardiac emergencies
Systems of care in cardiac emergencies
Associate Professor Dion Stub, Institution: Monash University...
Returning to work after a heart attack
Returning to work after a heart attack
Returning to work after a heart attack
Discover how to plan for your return to work....
Ranch burger bowls
Ranch burger bowls
Ranch burger bowls
Lamb recipes
Lamb recipes
Lamb recipes
Find heart healthy lamb recipes....
Easy chicken nasi goreng
Easy chicken nasi goreng
Easy chicken nasi goreng
Reading food labels
Reading food labels
Reading food labels
Nutrition information panels and ingredients lists are a good way of comparing similar foods so you can choose the healthiest option....
Prawn and avocado salad
Prawn and avocado salad
Q&A with A/Prof Seana Gall
Q&A with A/Prof Seana Gall
Q&A with A/Prof Seana Gall
Improving the prevention and management of stroke...
Sorting out your finances after a heart attack
Sorting out your finances after a heart attack
Sorting out your finances after a heart attack
Explore how to manage your financial concerns after a heart attack. ...
HEART FOUNDATION WELCOMES WALKING FUNDING
HEART FOUNDATION WELCOMES WALKING FUNDING
30 March 2022 ...
Hypertension clinical information and guidelines
Hypertension clinical information and guidelines
Clinical information for diagnosis and management of hypertension....
Taking your heart medicines
Taking your heart medicines
Taking your heart medicines
Know what your heart medicines are for and how to take them. ...